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KMID : 1146920200500040349
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Journal of Pharmaceutical Investigation
2020 Volume.50 No. 4 p.349 ~ p.361
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Recent developments in cancer therapy and diagnosis
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Atlihan-Gundogdu Evren
Ilem-Ozdemir Derya
Ekinci Meliha
Ozgenc Emre
Demir Emine Selin
Sanchez-Dengra Barbara
Gonzalez-Alvarez Isabel
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Abstract
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Background: The cancer is serious health problem and leading cause of death in the world.
Area covered: There have intensively studied for diagnosis and therapy of this disease and these studies provided important insights into their mechanism of action and therapeutic/diagnostic effects. The accurence rates of cancer has dramatic increase, particularly in the developed countries. Although there are many different strategies about diagnosis and treatment for cancer, more effective new approaches are needed.
Expert opinion: In this review, we summarize recent developments on cancer diagnosis, radiopharmaceuticals in cancer diagnosis, nanoparticulate systems in cancer diagnosis, T cells in cancer diagnosis, cancer therapy and pharmacokinetic of anticancer drugs. We thought that while there are some current limitations such as clinical studies, ranging from diagnosis to theraphy, future improvements in cancer diagnosis and treatment will meet the most relevant issues required for the eventual approval of nano-drugs, radiopharmaceuticals, T cells in clinical practice.
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KEYWORD
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Cancer, Diagnosis, Therapy, Radiopharmaceuticals, Nanoparticles, T-cells, Pharmacokinetics
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